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- 1. Multiple Choice
State the chemical nature of hemoglobin
Lipid
Polysaccharide
Polypeptide
Triglyceride
- 2. Multiple Choice
State which cell contains hemoglobin
Neutrophils
Erythrocytes
Lymphocytes
Mast cells
- 3. Multiple Choice
Refers to the nature of blood plasma
Consists mostly of water
Nonpolar
Hydrophobic
Consists of solid particles such as blood cells
- 4. Multiple Choice
Which of the following is true about the structure of hemoglobin?
Consists of 4 subunits called globular proteins
Heme groups are hydrophilic regions
Overall structure allows conformational changes
Tertiary-structured protein
- 5. Multiple Choice
Describe the nature of movement of oxygen within the blood and surrounding tissues
Moves down its electrochemical gradient
Moves down its partial pressure
Requires protein channels to diffuse across membranes
Moves out into the alveolar space from the capillaries
- 6. Multiple Choice
This best describes positive cooperativity of hemoglobin
As 1 O2 binds to a heme group, it causes a sudden shift of polarity, attracting more O2
As 1 O2 binds to a heme group, a conformational change occurs, making it more likely for additional O2 to bind
As 1 O2 binds to a heme group, hemoglobin becomes slightly less hydrophilic
As 1 O2 binds to a globin group, the binding site of O2 within the molecule becomes more exposed
- 7. Multiple Choice
Which is an accurate description of the overall environment between blood cells and surrounding tissues?
The PO2 in the capillaries is lower than in surrounding tissues
The PO2 in the capillaries is higher than in the surrounding tissues
- 8. Multiple Choice
State the curve of this graph
Exponential
Bell-shaped
Parabolic
Sigmoidal
- 9. Multiple Choice
In what point in the graph shows the condition of Hb within the alveoli?
Point 1
Point 2
Point 3
- 10. Multiple Choice
What explains the steep slope of the curve?
Binding of O2 within the heme groups
O2 loading into hemoglobin
Unloading of O2 from hemoglobin
Positive cooperativity
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