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- 1. Multiple Choice
Which of the following substances is found in
the dense granules of platelets?
Platelet-derived Growth Factor
von Willebrand factor
Serotonin
Fibrinogen
- 2. Multiple Choice
Which of the following statements is correct regarding the platelet membrane?
The lipid layer is comprised mainly of phospholipids
Thrombin facilitates binding to sub-endothelium
Platelet phospholipid facilitates binding of Factor XII
Thromboxane is made from membrane glycoproteins
- 3. Multiple Choice
Which of the following substances promotes platelet activation?
Protein S
Prostacyclin
Nitric Oxide
ADP
- 4. Multiple Choice
What is the three step process that stops blood flowing from a cut called?
haemostasis
homeostasis
coagulation
agglutination
- 5. Multiple Choice
What is the name of the protein that is released by platelets in response to an injury?
haemoglobin
glucose
fibrin
carbon dioxide
- 6. Multiple Choice
The exposure of tissue factor to blood starts which process?
platelet adhesion
platelet aggregation
the coagulation cascade
vasoconstriction
- 7. Multiple Choice
What is the name of the soluble factor that results in fibrinolysis?
plasmin
tissue plasminogen activator
fibrin degradation product
alpha 2 antiplasmin
- 8. Multiple Choice
Which pathway is represented by the diagram shown?
Extrinsic pathway
Intrinsic pathway
Common pathway
none of the above
- 9. Multiple Choice
Which of the following clotting factors are activated by thrombin? Select all that apply
Factor V
Factor X
Factor XIII
Factor XI
- 10. Multiple Choice
A 4-year-old male is seen at the University Hospital for recurrent joint bleeds. Coagulation tests revealed: PT 14/11 sec, PTT 47/29 sec. Which of the following coagulation factor deficiencies is compatible with this result?
Factor X
Factor IX
Factor V
Factor XIII
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