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- Multiple ChoicePlease save your changes before editing any questions.
Statement I: The strand with polarity 3'-5' only acts as the template during DNA replication.
Statement II: The newly synthesized strand is polymerized in 3'-5' polarity
Only statement I is false
Only statement I is true
Both the statements are true
Both the statements are false
- Multiple ChoicePlease save your changes before editing any questions.
The enzyme responsible for formation of RNA primer on lagging strand during DNA replication is
Primase
DNA depedent DNA polymerase
DNA dependent RNA Polymerase
Both A and C
- Multiple ChoicePlease save your changes before editing any questions.
The unwinding of DNA helix at ORI region is done by
Primase
Ligase
Helicase
SSBP
- Multiple ChoicePlease save your changes before editing any questions.
Which of the following is not correct in relation to topoisomerase II?
It cut both the strands of DNA at same time and ligate them after removing supercoiling
Its function is to remove supercoiling in front of replication fork
It always work in association with RNA primase
It relieves the tension from the DNA generated due to unwinding of by helicase
- Multiple ChoicePlease save your changes before editing any questions.
DNA replication,
Occurs during the S and G0 phase of Interphase
Is associated with the condensation of DNA into Chromosomes
is an enzyme mediated process that occurs in both prokaryotes and eukaryotes
is more prone to errors as enzymes used are not specialized for proofreading
- Multiple ChoicePlease save your changes before editing any questions.
E. coli DNA Polymerase I differs from DNA polymerase III in that the former has
3'-5' exonuclease activity
5'-3' exonuclease activity
5'-3' polymerisation activity
3'-5' DNA reading activity
- Multiple ChoicePlease save your changes before editing any questions.
The discontinuously synthesized strand,
is polymerized in 3'-5' direction
is polymerized entirely by DNA Pol. I
is also called as leading strand
is the one which possess okazaki fragments.
- Multiple ChoicePlease save your changes before editing any questions.
Identify the mismatch pair.
DNA Ligase - joins discontinuous framents later
Primase - formation of okazaki fragments
DNA Polymerase III - Polymerization of new daughter strand
SSBP - Stabalizes single strand DNA of replication fork
- Multiple ChoicePlease save your changes before editing any questions.
Which of the following is correct with respect to DNA replcation?
Enzyme Helicase is used to stabilize the ssDNA s
Enzyme ligase is used to employ RNA primers
Enzyme DNA Pol. I is the main polymerizing enzyme
Okazaki fragments are made up of deoxynucleotides
- Multiple ChoicePlease save your changes before editing any questions.
For the strand separation and stabilisation during DNA replication which of the following set of enzymes and proteins are required?
SSBP, gyrase, primase
Topoisomerase, helicase, ligase
Gyrase, ligase, primase
Topoisomerase, helicase, SSBP
- Multiple ChoicePlease save your changes before editing any questions.
During replication of a bacterial chromosome DNA synthesis starts from a replication origin site and
DNA primers are involved
is facilitated by telomerase
moves in one direction of the site
moves in bi-directional way
- Multiple ChoicePlease save your changes before editing any questions.
Select the correct match of enzyme with its related function.
DNA polymerase – Synthesis of DNA strands
Helicase – Unwinding of DNA helix
Ligase – Joins together short DNA segments
All of these
- Multiple ChoicePlease save your changes before editing any questions.
A wrong base if added, is removed and replaced with a proper base during DNA replication by
DNA polymerase I
DNA polymerase II
DNA polymerase III
RNA primer
- Multiple ChoicePlease save your changes before editing any questions.
In a double stranded DNA molecule the percentage of cytosine is 18, what will be percentage of bicyclic nitrogen bases?
50%
36%
64%
18%
- Multiple ChoicePlease save your changes before editing any questions.
Which of the following enzymes has exonuclease activity in 3’ to 5’ as well as in 5’ to 3’ direction?
DNA polymerase I
DNA polymerase III
RNA polymerase III
All of the above