10 questions
Which of the following is an eg of g protein coupled receptor?
Insulin receptor
Adrenergic Receptor
EGFR
Calcium gated channel
Which of the following is an eg of receptor tyrosine kinase? you can pick > 1 ans
Insulin receptor
Adrenergic Receptor
EGFR
Calcium gated channel
Gαs stimulates adenylyl cyclase (AC) and increases cyclic AMP (cAMP) levels.
True or false?
True
False
Gαi family members activate phospholipase C (PLC), which cleaves phosphatidylinositol bisphosphate (PIP2) into diacylglycerol and inositol triphosphate (IP3). True or False
False
True
RTKs have how many transmembrane domain?
1
3
5
7
For RTKs, cis-autoinhibition occurs when ____?
ligand binds to RTK
there is no ligand
when g protein is active
Which domains bind to RTKs after ligand binding? you can pick > 1 ans
SH2 domain
PTB domain
ATP domain
activation of PLC by GPCRs to generate the two second messengers, which are? you can pick > 1 ans
cAMP
DAG
IP3
PIP2
most common calcium-binding motifs are? you can pick > 1 ans
EF hands
C2 domain
SH2 domain
ATP domain
Phosphorylation adds a phosphate group to ______, threonine, and tyrosine residues in a protein, changing their shapes, and activating or inactivating the protein
Serine
glycine
alanine
cysteine