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Chemistry, Science, Professional Development
University -
Professional Development
Medicinal Chemistry
12 questions
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- 1. Multiple Choice
Name the linkage (or) bridge present in the structure of Artemisinin?
Ester
Peroxide
Epoxide
Glycosidic linkage
- 2. Multiple Choice
Pyrimethamine has the following IUPAC name:
2, 4-diamino-6-ethyl-5-(p-chlorophenyl) pyrimidine
2, 4-diamino-6-ethyl-5-(p-chlorophenyl) pyridine
2, 4-diamino-6-ethyl-5-(m-chlorophenyl) pyrimidine
2, 4-diamino-6-ethyl-5-(o-chlorophenyl) pyrimidine
- 3. Multiple Choice
Isoniazid inhibits the mycolic acid synthesis by acting on which enzyme ?
DNA dependent RNA Polymerase
DNA gyrase
Mycolase synthatase
RNA polymerase
- 4. Multiple Choice
1. At which position carboxylic acid functional group is present in fluoro quinolones?
2
5
4
3
- 5. Multiple Choice
Iodoxuridine chemically is -----------
2’-Deoxy-5-iodoxuridine
3’-Deoxy-5-iodoxuridine
2’-oxy-5-iodoxuridine
3’-oxy-5-iodoxuridine
- 6. Multiple Choice
Which element is present in the Foscarnet structure?
Ferrous
Fluorine
Phosphorous
Sulphur
- 7. Multiple Choice
Which nitro imidazole derivative has morpholino moiety?
Tinidazole
Ornidazole
Timorazole
Metronidazole
- 8. Multiple Choice
IUPAC name for metronidazole is
2-(2-methyl-5-nitro-1H-imidazol-1-yl)- methanol
2-(2-methyl-5-nitro-1H-imidazol-1-yl)- ethanol
2-(2-nitro-5-methyl-1H-imidazol-1-yl)- methanol
2-(2-nitro-5-methyl-1H-imidazol-1-yl)- ethanol
- 9. Multiple Choice
The raw material used for the synthesis of diethyl carbamazine is
Toulene
N- methyl Piperazine
3,4,5 – trimethoxy benzaldehyde
N- methyl Pyridine
- 10. Multiple Choice
Heterocyclic system present in Diethyl carbamazine is
Piperazine
Piperidine
Pyrrolidine
Pyridine
- 11. Multiple Choice
The ratio of sulphamethoxazole and trimethoprim in Co-trimoxazole.
1:2
2:1
1:5
5:1
- 12. Multiple Choice
Sulfasalazine is beneficial in ulcerative colitis. Which is responsible for this action? Identify.
Sulfasalazine
Its metabolic product, sulfapyridine
Its metabolic product, amino salicyclic acid
Any of the above
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