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- 1. Multiple Choice
Which of the following was NOT a goal of the Human Genome Project?
To determine the sequence of the human genome
To determine how DNA could be used forensically
To develop new tools to obtain and analyze DNA data
To store the sequencing information in a database
- 2. Multiple Choice
Approximately, how many base pairs are in the human genome?
23,000
23
3 million
3 billion
- 3. Multiple Choice
Which best defines the term, "gene"?
a heritable factor that consists of a length of DNA and influences a specific characteristic
a heritable factor that consists of a length of mRNA and influences many characteristics
a heritable factor that consists of a length of DNA and influences many characteristics
a heritable factor that consists of a length of mRNA and influences a specific characteristic
- 4. Multiple Choice
What is it called when the order of DNA nucleotides is determined for a section of DNA?
DNA sequencing
Denaturation
Gel Electrophoresis
DNA replication
- 5. Multiple Choice
In the Sanger sequencing method, what causes the termination of each chain of DNA?
The incorporation of a deoxynucleotide
When the DNA polymerase encounters a stop codon
The incorporation of a dideoxynucleotide
Denaturation of the double strand
- 6. Multiple Choice
New alleles result from
New cells
Cell division
Mutations
New chromosomes
- 7. Multiple Choice
Comparing DNA sequences between species can help us determine
degree of similarity between species
evolutionary relationships
Differences in base sequences
all of the answers apply
- 8. Multiple Choice
Which is the correct order from LARGEST genome to SMALLEST
T2 Phage, E. coli, Drosophila melanogaster, Homo sapiens, Paris japonica
Paris japonica, Homo sapiens, Drosophila melanogaster, E. coli, T2 Phage.
Paris japonica, Homo sapiens, E. coli, Drosophila melanogaster, T2 Phage.
Drosophila melanogaster, T2 Phage, Paris japonica, Homo sapiens, E. coli,
- 9. Multiple Choice
In an electropherogram, the different colored peaks correspond to
proteins
genes
nucleotide bases
traits
- 10. Multiple Choice
Sickle cell disease is caused by a
base substitution mutation
frameshift mutation
nonsense mutation
silent mutation
- 11. Multiple Choice
The specific position of a gene on a chromosome is called?
species
gene
locus
allele
- 12. Multiple Choice
What is the difference between a deoxynucleotide and a dideoxynucleotide?
A deoxynucleotide is missing a 3'-hydroxyl group on its sugar.
A dideoxynucleotide is missing a 3'- hydroxyl group on its sugar.
A deoxynucleotide is missing a 5'-phosphate group.
A dideoxynucleotide is missing a 5'-phosphate group
- 13. Multiple Choice
What determines the genomic size of a species?
The total amount of DNA
The total number of genes
The total number of alleles
The total number of chromosomes
- 14. Multiple Choice
What is the cause of sickle-cell anemia?
A change to the base sequence of a hemoglobin gene
Mosquitos acting as the vector for malaria
Iron deficiency due to the malaria parasite
Production of more white blood cells than red blood cells by bone marrow
- 15. Multiple Choice
Which of the following is the cause of sickle-cell anemia?
Tryptophan is replaced by leucine
Leucine is replaced by valine
Glutamic acid is replaced by valine
Lysine is replaced by glutamic acid
- 16. Multiple Choice
What distinguishes an allele from a gene?
An allele is made of RNA
An allele is shorter
An allele is a variety of a gene
An allele cannot be transferred during genetic modification
- 17. Multiple Choice
A genome is.....
the total of all the genetic information an organism has
the number of chromosomes an organism has
the mechanism by which an individual passes on genetic information
a small garden statue belonging to a frenchman
- 18. Multiple Choice
True or false, the number of genes is determined by the complexity of the organism?
- 19. Multiple Choice
Which of the following is TRUE?
Homo sapiens have approximately 23,000 genes, Daphnia pulex (water fleas) have 31,000 genes.
Rice plants have less genes than humans
Less complex organisms have less genes than more complex organisms
It is impossible to approximate the number of genes in an organism.
- 20. Multiple Choice
What type of mutation causes sickle cell anemia?
Base substitution
Base deletion
Base insertion
All of these types of mutation
- 21. Multiple Choice
How are new alleles formed?
By random mutation
By pre-determined mutation
During protein synthesis
New alleles can never be formed
- 22. Multiple Choice
How is DNA synthesis in PCR and Cycle Sequencing the SAME?
Both require DNA polymerase.
Both require primers.
Both require deoxynucleotides (dNTPs).
Both require dideoxynucleotides (dNTPs).
Both generate new DNA products of equal length.
- 23. Multiple Choice
How are deoxyribonucleotides different from dideoxyribonucleotides? Choose all that apply.
Deoxyribonucleotides are used in both PCR and Cycle Sequencing.
Dideoxyribonucleotides are missing an OH group compared to deoxyribonucleotides.
You cannot add new nucleotides to a deoxyribonucleotide.
Deoxyribonucleotides are NOT found in natural living cells.
Dideoxyribonucleotides are labeled with fluorescent tags.
- 24. Multiple Choice
What do dideoxynucleotides do when added to a growing DNA strand during Cycle Sequencing?
They stop the elongation of that strand.
That double the length of that strand.
They shorten the length of the strand.
They denature the strand.
- 25. Fill in the Blank
Write the correct sequence that matches this chromatogram.
- Answer choicesTagsAnswer choicesTags