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35 questions
What does MPF stand for?
Maternity-Parental Factor
Mitosis-Parent Factor
Mitosis-Protecting Factor
Maturation-Promoting Factor
MPF activity is high in early G2 and low in mitosis.
True
False
What enzymatic activity do MPF involve?
synthesis of amino acids
Phosphorylation
Promoting-related factor
Transcription of DNA
MPF is a positive regulator because it stimulates cell cycle processes.
True
False
I don't know
What organisms did scientists use for the research on discovering cyclins?
Sea urchins and fish
Fish and clam
Sea urchins only
sea urchins and clam
What is MPF composed of? (2 answers)
cyclin and kinases
kinases and cdc2 proteins
cyclin and cdc2 proteins
Cdk only
A protein kinase enzyme that is only active when complexed with cyclin is called ____________
Cylin kinase enzyme
Kinase dependent enzyme
Cyclin dependent kinase
Kinase Cyclin Combination
During what checkpoint does MPF activate the most?
G1 checkpoint
G2 checkpoint
M-spindle checkpoint
Not sure
During when do p53 genes check for damaged DNA?
G1 checkpoint
G2 checkpoint
M-spindle checkpoint
not sure
One of the examples of growth factors is ________
PDFG
PDPF
MDPF
MFGP
p53 gene is considered a tumor-promoting gene.
True
False
All cancer cells must contain nonfunctional p53.
True
False
What are the genes that can cause cells to become cancer cells called?
Oncogenes
Oocytes
proto-oncogenes
Post-oocytes
Which of the following is not an example of tumor-suppressor gene?
p53 gene
Rb gene
cdc2 gene
What is the lump of abnormal cells that remain at original site called?
benign tumor
malignant tumor
tumors
cancer cells
Cancer is...
Uncontrolled cell growth
Normal cell growth
A protein
A cell cycle regulator
A substance that is known to cause cancer is called a
pathogen
carcinogen
retrovirus
paramecium
Which of these is a tumor that is noncancerous and does not spread?
Malignant
Benign
Be nice
normal tumor
Which of the following is a type of protein that regulates the cell cycle?
actin
myosin
cyclin
pepsin
Which of the following shows the correct sequence of the cell cycle?
Mitosis-> G1->S->G2->cytokinesis
cytokinesis->mitosis->G1->S->G2
S->G1-> G2-> mitosis-> cytokinesis
G1->S->G2->mitosis->cytokinesis
How does mitosis in plant cells differ from mitosis in animal cells?
animal cells form a cell plate
plant cells form a cell plate
plant cells go through the process in reverse
plant cells go through two rounds of mitosis while animal cells just do one
In which phase of mitosis do the sister chromatids line up on the equator of the cell?
Prophase
Metaphase
Anaphase
Telophase
In which phase of mitosis does the nucleus disappear, centrioles move to the poles, and chromosomes condense into sister chromatids?
Prophase
Metaphase
Anaphase
Telophase
Why do cells go through cell division
Growth
Reproduction
Repair
All of the above
Chromosome movement in mitosis and meiosis is regulated by
microtubules
microfilaments
intermediate filaments
All of these
Which of the following happens when a cell divides?
The cell has DNA overload.
The cell’s volume increases.
Each daughter cell receives its own copy of the parent cell’s DNA.
It becomes more difficult for the cell to get enough oxygen and nutrients.
________________is a critical point where stop and go signals can regulate the cycle
Metastasis
Checkpoint
Malignant
Benign
Type of tumor that remains at original site
Benign
Metastaasis
Malignant
checkpoint
When cancer spreads to other areas of the body, it is said to have
metastisized
benigned
tumored
localized
Which of these is a risk factor for developing cancer?
growing older
genetic inheritance
exposure to carcinogens (toxins that can damage DNA)
all of the above
The normal function of a tumor suppressor gene is
to produce growth signals
to code for proteins that inhibit, or slow, cell division
to cause the cell to move faster through the cell cycle
to attack cancer cells in the body
What are cyclins and cyclin dependent kinases?
regulatory proteins
mitotic proteins
carcinogens
mutagens
What type of gene prevents the cells with damage from continuing through the cell cycle?
tumor suppressor
stem cell suppressor
proto-oncongene
stem cell initiator
A type of CdK-cyclin complex that promotes mitosis and peaks in concentration at the end of mitosis.
p53
Platelet Derived Growth Factor (PDGF)
Rb gene
Maturation (Mitosis) Promoting Factor (MPF)
Halts cell division if it detects damaged DNA; can either fix, force G0 , or apoptosis.
Rb
PDGF
p53
MPF
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