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30 questions
Cyclin D.....
triggers cells to move from G0 to G1 and from G1 to S phase. Phosphorylates a protein which is a tumor suppressor.
phosphorylates a target protein which prepares DNA for replication.
in S phase initiates DNA replication and in G2 phase prepares two centrioles for mitosis.
promotes the assembly of the mitotic spindle and other tasks in preparation for mitosis, but inhibits anaphase until the cyclin has been degraded.
Cyclin E.....
triggers cells to move from G0 to G1 and from G1 to S phase. Phosphorylates a protein which is a tumor suppressor.
phosphorylates a target protein which prepares DNA for replication.
in S phase initiates DNA replication and in G2 phase prepares two centrioles for mitosis.
promotes the assembly of the mitotic spindle and other tasks in preparation for mitosis, but inhibits anaphase until the cyclin has been degraded.
Cyclin A.....
triggers cells to move from G0 to G1 and from G1 to S phase. Phosphorylates a protein which is a tumor suppressor.
phosphorylates a target protein which prepares DNA for replication.
in S phase initiates DNA replication and in G2 phase prepares two centrioles for mitosis.
promotes the assembly of the mitotic spindle and other tasks in preparation for mitosis, but inhibits anaphase until the cyclin has been degraded.
Cyclin B.....
triggers cells to move from G0 to G1 and from G1 to S phase. Phosphorylates a protein which is a tumor suppressor.
phosphorylates a target protein which prepares DNA for replication.
in S phase initiates DNA replication and in G2 phase prepares two centrioles for mitosis.
promotes the assembly of the mitotic spindle and other tasks in preparation for mitosis, but inhibits anaphase until the cyclin has been degraded.
What action do CDKs perform on target proteins?
They make allosteric changes by binding to the protein.
They add a methyl group to the protein.
They remove a methyl group from the protein.
They add a phosphate group to the protein.
They remove a phosphate group from the protein.
Which statement about the relationship between cyclins and CDKs is true?
CDKs activate cyclins.
CDKs repress cyclins.
Cyclins activate CDKs.
Cyclins repress CDKs.
Cyclins and CDKs do not interact.
What type of biomolecule are cyclins?
Carbohydrates
Lipids
Proteins
Steroids
What type of enzymes are kinases?
They add phosphate groups to other biomolecules
They add protein groups to other biomolecules
They add carboxyl groups to other biomolecules
They add amino groups to other biomolecules
What happens to cyclins at the end of their cycle?
They are recycled and used again
They are degraded
They reach a low level and remain there until they are needed, then they increase to their optimum level
They stay at a constant level throughout the cell cycle
Two internal factors that are important in advancing the cell cycle are
kinases and cyclins.
hormones and enzymes.
phosphates and enzymes.
proteins and platelets
The specific molecular control signal substances in the cytoplasm of cells are proteins known as.....
kinases & cyclins
enzymes & cytosines
helicases & ligases
polymerases & primases
In which stage are cells more susceptible to mutations?
G1
S
G2
G0
The cell cycle is made up of 2 main stages, interphase and mitosis. What are the phases of interphase?
Prophase, Metaphase, Anaphase, Telophase
S1, G, S2
G1, S, G2
G1, G0, G2
The uncontrolled growth of a cell is due to.....
too many organelles
cells getting too big
cells behaving abnormally
all of the above
Why does chemotherapy cause nausea and a person's hair to fall out?
The dying tumor cells cause these effects on the body
Chemotherapy kills all rapidly dividing cells in the body
These are effects of the cancer and not from the chemotherapy
The chemotherapy stops all cell division within a cell
_____________ is the process of malignant cells getting into the circulatory system and establish colonies in other parts of the body.
Tumor
Uncontrolled growth
Cancer
Metastasis
A student view onion cells under a microscope and notices the cells are reproducing by mitosis. Which hypothesis is supported by this?
the cells all have the same chromosomes
the cells each have a unique genetic make-up
the cells produce identical gametes
the cells split to form stem cells
Why are cancer cells not identified by white blood cells?
Because they hide
Because they grow too quickly
Because they look like our own cells
Because they fly by too quickly
Who won the Nobel Prize in 2001 for serendipitously discovering cyclins?
Tim Horton
Tim Hunt
James Hunt
James Watson
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