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- 1. Multiple ChoiceBecause DNA is a highly charged polyanion, its stability to heat denaturationdoes not depend on hydrophobic interactionsincreases with increasing saltis independent of G - C contentdecreases with increasing salt
- 2. Multiple ChoiceThe sugar in RNA is __________ , the sugar in DNA is __________deoxyribose, riboseribose, deoxyriboseribose, phosphateribose, uracil
- 3. Multiple ChoiceNucleoside is a pyrimidine or purine basecovalently bonded to a sugarionically bonded to a sugarhydrogen bonded to a sugarnone of the above
- 4. Multiple ChoiceIn gel electrophoresis, what fragments will move most quickly through a gel?Large fragmentsSmall fragmentsLarge genomeNone of thes
- 5. Multiple ChoiceWhich pyrimidine base contains an amino group at carbon 4?CytosineThymineUracilAdenine
- 6. Multiple ChoiceThe glycosidic bonds in DNA and RNAconnect the sugar to the basecan be hydrolyzed by OH- ionstabilize Watson-Crick H-bondsare free to rotate over about 180°
- 7. Multiple ChoiceNucleic acids can be analyzed experimentally by theirmolecular weightabsorption of visible lightabsorption of uv lightnone of these
- 8. Multiple ChoiceThymidinecan participate in hydrophobic interactions due to its methyl groupis replaced by uracil in RNAnormally forms two hydrogen bonds with adenosineall of the abov
- 9. Multiple ChoiceA nucleotide consists ofa sugar, a base and a phosphatea sugar and a phosphatepaired basesa sugar, a base and three phosphates
- 10. Multiple ChoiceA five carbon sugar lacking a hydrogen at the number 2 carbon is found inDNARNAmRNArRNA
- 11. Multiple ChoiceThe most stabilizing force for nucleic acids ishydrogen bondselectrostatic bondVan der Waalsconformational entropy
- 12. Multiple ChoiceWhich of the following is found on RNA but not DNA?UracilDeoxyribosePhosphateAdenine
- 13. Multiple ChoiceWhich of the following is a purine?CytosineAdenineThymineUracil
- 14. Multiple ChoiceChargaff's rule states that in a double strandedDNA moleculeConc. Of A nucleotides equals to that of T nucleotidesConc. Of A nucleotides equals to that of G nucleotidesConc. Of Cnucleotides equals to that of T nucleotidesConc. Of U nucleotides equals to that of Gnucleotidesall of the above
- 15. Multiple ChoiceChoose the incorrect statement of the followingDouble stranded DNA exist atleast in six forms(A-E)&ZB form is usually found in the physiologic formSingle turn of B-DNA about the axis of the molecule contains six bpThe distance spanned by one turn of B DNA is 3.4nmThe helical diameter of double helix in B-DNA is 2 cm
- 16. Multiple ChoiceWhen the DNA molecule is twisted in the direction opposite from the clockwise turns of the right handed double helix found in B-DNA such DNA said to have acquiredZ formA formpositive supercoilsnegative supercoilsno change
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